| Southern Ocean Whale Sanctuary | 50,000,000 km² | 1,994 | Southern Ocean (Antarctic) | All baleen whales | Covers the whole of the Antarctic Ocean. The largest IWC sanctuary. |
| Indian Ocean Whale Sanctuary | 5,500,000 km² | 1,979 | Indian Ocean | All baleen whales | Inter-state IWC sanctuary: commercial whaling banned. |
| Marae Moana | 1,900,000 km² | 2,017 | Cook Islands (Pacific) | Humpback whale, sperm whale, false killer whale, pilot whale | The largest MPA in the world. |
| Ross Sea MPA | 1,550,000 km² | 2,017 | Antarctica | Type C killer whales, common minke whales | Largest marine sanctuary in the Southern Ocean. |
| Papahānaumokuākea Marine NM | 1,500,000 km² | 2,006 | NW Hawaii (USA) | Humpback whale, Hawaiian monk seal | Largest MPA in the United States. |
| Phoenix Islands Protected Area | 408,000 km² | 2,008 | Kiribati (central Pacific) | Sperm whale, tropical dolphins | UNESCO site. Covers little-disturbed pelagic ecosystems. |
| Great Barrier Reef Marine Park | 344,400 km² | 1,975 | Australia | Humpback whale (breeding season), dugongs | Includes the South Pacific humpback migration. |
| Agoa Sanctuary | 138,000 km² | 2,010 | the French Antilles | Humpback whale (breeding), sperm whale, pilot whale | Covers the waters of the French Antilles (Guadeloupe, Martinique). |
| Galápagos Marine Reserve | 138,000 km² | 1,998 | Ecuador | Blue whale, sperm whale, killer whale, common dolphin | One of the most diverse MPAs in the world. |
| Niue Marine Park | 127,000 km² | 2,020 | Niue (S Pacific) | Humpback whale, sperm whale, spinner dolphin | Small nation, large ambition (40% no-take). |
| Bijagós Archipelago MPA | 88,600 km² | 1,996 | Guinea-Bissau | Seahorse, Atlantic humpback dolphin | UNESCO Man and the Biosphere reserve. |
| Pelagos Sanctuary | 87,500 km² | 1,999 | NW Mediterranean (France/Italy/Monaco) | Fin whale, sperm whale, striped dolphin + 5 others | The world's first high seas MPA dedicated to cetaceans. |
| Southern Right Whale Sanctuary | 50,000 km² | 2,003 | Argentina (Patagonia) | Southern right whale | Includes Peninsula Valdés (UNESCO). |
| Glacier Bay National Park | 13,287 km² | 1,980 | Alaska (USA) | Humpback whale, killer whale | UNESCO site. |
| Bocas del Toro Whale Sanctuary | 7,800 km² | 2,009 | Panama (Caribbean) | Humpback whale | Breeding site for wintering humpback whales. |
| Whale Valley Coastal MPA | 5,000 km² | 2,016 | Caribbean coast of Colombia | Humpback whale | Colombian breeding site (July-November season). |
| Channel Islands NMS | 3,800 km² | 1,980 | California (USA) | Blue whale, fin whale, grey whale | Upwelling zone feeding baleen whales. |
| Hawaiian Islands Humpback Whale NMS | 3,600 km² | 1,992 | Hawaii | Humpback whale (breeding) | Main breeding site of the North Pacific pop. |
| Stellwagen Bank NMS | 2,200 km² | 1,992 | Massachusetts (USA) | Humpback whale, North Atlantic right whale, common minke whale | Breeding and feeding ground for the NW Atlantic humpback whale pop. |
| Banco Chinchorro | 1,440 km² | 1,996 | Quintana Roo (Mexico) | Common bottlenose dolphin, spotted dolphin | Caribbean atoll home to cetaceans and sharks. |
| Saguenay-Saint-Laurent Marine Park | 1,245 km² | 1,998 | Quebec (Canada) | Beluga (resident), fin whale, common minke whale, blue whale | Unique resident beluga pop. in the St Lawrence. |
| Spermwhale Sanctuary Dominica | 790 km² | 2,024 | Dominica (Caribbean) | Sperm whale (resident, ~250 ind.) | First sanctuary dedicated TO sperm whales (announced Nov. 2023, created 2024). |
| Cabo Pulmo National Park | 710 km² | 1,995 | Baja California Sur (Mexico) | Blue and humpback whales on migration | Exemplary recovery of a marine ecosystem. |